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THROMBORESISTANT/BACTERICIDAL S-NITROSO-N-ACETYLPENICILLAMINE (SNAP)-DOPED NITRIC OXIDE RELEASE POLYMERS WITH ENHANCED STABILITY
专利权人:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
发明人:
BRISBOIS, ELIZABETH, J.,HANDA, HITESH,MEYERHOFF, MARK, E.
申请号:
EP14748530
公开号:
EP2953660A4
申请日:
2014.02.06
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
A polymeric film includes a polymer matrix having at least one of a discrete RSNO adduct or a polymeric RSNO adduct associated therewith, by: covalent attachment to the polymer matrix dispersion within the polymer matrix or both, with the at least one of the discrete RSNO adduct or the polymeric RSNO adduct capable of releasing nitric oxide (NO). The polymer matrix is a polyurethane polymer matrix, a silicone rubber polymer matrix, or a copolymer matrix of polyurethane and silicone rubber. The polymeric film is to exhibit stability under dry conditions at 37° C. and prolonged and controllable NO release rates, when exposed to moisture or light capable of photolyzing an RSNO bond, for a predetermined amount of time from the at least one of the discrete RSNO adduct or the polymeric RSNO adduct.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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