Chiang Li,Johannes Heinrich Fruehauf,Shuanglin Xiang
申请号：
US13196436
公开号：
US20120093773A1
申请日:
2011.08.02
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Methods are described for the delivery of one or more small interfering RNAs (siRNAs) to a eukaryotic cell using a bacterium. Methods are also described for using this bacterium to regulate gene expression in eukaryotic cells using RNA interference, and methods for treating cancer of cell proliferative disorders. The bacterium includes one or more siRNAs or one or more DNA molecules encoding one or more siRNAs. Vectors are also described for use with the bacteria of the invention for causing RNA interference in eukaryotic cells.
