PROFESSIONAL COMPOUNDING CENTERS OF AMERICA (PCCA)
发明人:
VU, CHRISTINE,BANOV, FABIANA CAMPANATI VIEIRA,BANOV, DANIEL
申请号：
CA2958925
公开号：
CA2958925A1
申请日:
2015.08.20
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present disclosure refers to a synergistic blend of Konjac powder and Xanthan gum that is included, as a natural suspending agent, in oral pharmaceutical suspensions. Oral pharmaceutical suspensions comprising the synergistic blend are aqueous solutions. The synergistic blend, used as a suspension agent to suspend suitable active pharmaceutical ingredients (APIs), improves the stability of oral pharmaceutical suspensions, and helps in the formation of a thermo-reversible gel and shear thinning necessary to keep APIs suspended within oral pharmaceutical suspensions. The synergistic blend of Konjac powder and Xanthan gum has unique anti-flocculation properties, which improve the homogeneity of the oral pharmaceutical suspensions. Additionally, the blend provides a better texture and mouth feel. Oral pharmaceutical suspensions, comprising the synergistic blend, include a vehicle, such as water, as well as different components, such as, for example APIs, preservatives, sweeteners, flavoring agents, and pH regulators or buffers, among others.
