Chitosan-based nanoparticles and methods for transfecting gut cells in vivo

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专利权人:

INC.;ENGENE

发明人:

HSU, ERIC,CHEUNG, ANTHONY T

申请号：

NZ57196507

公开号：

NZ571965A

申请日:

2007.03.30

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

A chitosan-based nanoparticle that comprises a plurality of chitosan polymers that have an average molecular weight between 3 kDa and 50 kDa, and encapsulates a construct. The construct comprises a nucleic acid that encodes a protein operably linked to an expression control region that is functional in a gut mucosal cell. The nanoparticle can be used to treat a disease by encoding a therapeutic protein.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/