HASSFELD JORMA,KINZEL TOM,KOBBERLING JOHANNES,CANCHO GRANDE YOLANDA,BEYER KRISTIN,ROHRIG SUSANNE,KOLLNBERGER MARIA,SPERZEL MICHAEL,BURKHARDT NILS,SCHLEMMER KARL-HEINZ,STEGMANN CHRISTIAN,SCHUHMACHER JO
申请号:
AP2016009175
公开号:
AP2016009175A0
申请日:
2014.11.03
申请国别(地区):
AP
年份:
2016
代理人:
摘要:
The present application relates to novel substituted (aza)pyridopyrazolopyrimidinones and indazolopyrimidinones, to processes for their preparation, the compounds for use alone or in combinations in a method for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of acute and recurrent bleeding in patients with or without underlying hereditary or acquired bleeding disorders, wherein the bleeding is associated with a disease or medical intervention selected from the group consisting of menorrhagia, postpartum hemorrhage, hemorrhagic shock, trauma, surgery, transplantation, stroke, liver diseases, hereditary angioedema, nosebleed, and synovitis and cartilage damage following hemarthrosis.