A medical monitoring device (12) includes a motion detection device (20, 50) and a vital sign monitoring device (26, 52) communicatively connected to the motion detection device. The motion detection device (20, 50) detects whole body motion of a person. The vital sign monitoring device (26, 52) monitors, either continuously or intermittently, at least one vital sign for a predetermined time interval in response to the detected whole body motion. The vital sign is evaluated, e.g. for orthostatic intolerance, and in response to an affirmative evaluation an alarm signal is issued.