SURFACE-MODIFIED NANOSPHERES ENCAPSULATING ANTIGEN-BINDING MOLECULES

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专利权人:

发明人:

申请号：

EP16805989.7

公开号：

EP3377115A2

申请日:

2016.11.17

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present invention relates to nanospheres which comprise a polymeric matrix and antigen-binding molecules esterase-releasably incorporated therein and are coated with targeting molecules which increase the cellular uptake of the nanospheres. The polymeric matrix is formed by poly(alkyl cyanoacrylates) and/or alkoxy derivatives thereof. The invention further relates to methods for preparing and compositions comprising such nanospheres.

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