The present invention relates to skin care compositions and methods of making said compositions, particularly topical compositions, comprising extract or juice from the plant Kalanchoe pinnata. The invention further concerns topical compositions comprising extracts from Kalanchoe pinnata and Kalanchoe daigremontiana plants for administration to human skin. The compositions are therapeutically effective for hydrating and conditioning the skin to improve its condition and are additionally shown to be effective at treating some dermal conditions or skin disorders, in particular, psoriasis, atopic dermatitis, allergic contact dermatitis, acne and herpes virus infection.