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T CELL RECEPTOR-DEFICIENT T CELL COMPOSITIONS
专利权人:
发明人:
申请号:
EP13784744.8
公开号:
EP2844742A1
申请日:
2013.04.30
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The invention is directed to modified T cells, methods of making and using isolated, modified T cells, and methods of using these isolated, modified T cells to address diseases and disorders. In one embodiment, this invention broadly relates to TCR-deficient T cells, isolated populations thereof, and compositions comprising the same. In another embodiment of the invention, these TCR-deficient T cells are designed to express a functional non-TCR receptor. The invention also pertains to methods of making said TCR-deficient T cells, and methods of reducing or ameliorating, or preventing or treating, diseases and disorders using said TCR-deficient T cells, populations thereof, or compositions comprising the same.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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