The present invention relates to an anti-atopic cream comprising: a first component comprising Houttuynia cordata, Acori gramineri Rhizoma, Saposhnikoviae Radix, Astragalus membranaceus Radix, Eriobotryae Folium, Sophorae flavescentis Radix, Saururus chinensis, Phellodendron bark, Centella asiatica, Arisaematis Rhizoma and Aster yomena and a second component comprising glycerol, a caprylic or capric triglyceride, sunflower seed oil, butylene glycol, butylene glycol dicaprylate or dicaprate, macadamia seed oil, polyglyceryl-3 methylglucose distearate, PEG-4 olivate, meadowfoam seed oil, dimethicone, cetyl ethylhexanoate, oxidized corn oil, cetearyl alcohol, tocopheryl acetate, glyceryl acrylate or acrylic acid copolymer, stearyl glycyrrhetinate, sodium chloride, sodium acrylate or sodium acryloyl dimethyl taurate copolymer, algin, isohexadecane, caprylyl glycol, polysorbate 80, allantoin, caprylhydroxamic acid, propylene glycol, disodium EDTA and ceramide 3 and, in the anti-atopic cream, the first component and the second component are mixed in a weight ratio of between 5:5 and 7:3. According to the present invention, when the anti-atopic cream is applied to a DNCB induced atopic dermatitis mouse, the blood IgE is reduced and at the same time the amount of discharged histamine produced from the mast cells is suppressed, thereby making it possible to provide an anti-atopic cream having a therapeutic effect in atopic dermatitis.La présente invention concerne une crème anti-atopique comprenant : un premier constituant comprenant Houttuynia cordata, Acori gramineri Rhizoma, Saposhnikoviae Radix, Astragalus membranaceus Radix, Eriobotryae Folium, Sophorae flavescentis Radix, Saururus chinensis, de lécorce dePhellodendron, Centella asiatica, Arisaematis Rhizoma et Aster yomena et un second constituant comprenant un glycérol, un triglycéride caprylique ou caprique, de lhuile de tournesol, du butanediol, un dicaprylate ou dicaprate de butanediol, de lhuile de macadamia, du