Robert H. GRUBBS;Vanessa M. MARX;CALIFORINA INSTITUTE OF TECHNOLOGY
发明人:
Vanessa M. Marx,Robert H. Grubbs
申请号：
US15737705
公开号：
US20180185272A1
申请日:
2016.06.20
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present disclosure is directed to fatty-acid glycerol ester derivative compounds containing a targeting bisphosphonate group. The disclosure further include pharmaceutical or biomedical compositions comprising these compounds, and methods of using these compounds and compositions forming microbubbles. The microbubbles have affinity for metal-containing, especially calcium-containing, bodies and/or biological targets. In certain embodiments, these compositions are useful for providing targeted placement of microbubbles capable of cavitation on application of high frequency energy.
