Grubbs, Robert H.;California Institute of Technology;Marx, Vanessa M.
发明人:
申请号：
EP16812640.7
公开号：
EP3310794A4
申请日:
2016.06.20
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
The present disclosure is directed to fatty-acid glycerol ester derivative compounds containing a targeting bisphosphonate group. The disclosure further include pharmaceutical or biomedical compositions comprising these compounds, and methods of using these compounds and compositions forming microbubbles. The microbubbles have affinity for metal-containing, especially calcium-containing, bodies and/or biological targets. In certain embodiments, these compositions are useful for providing targeted placement of microbubbles capable of cavitation on application of high frequency energy.
