606177 The disclosure relates to the use of ibuprofen in the manufacture of a medicament for prevention and treatment of actinic keratosis and pharmaceutical compositions for such purposes. The medicament disclosed maybe from 1 to 20% by weight ibuprofen and may contain the following as penetration enhancer’s dimethyl isosorbide, poloxamers, laurocapram, pyrrolidones, dimethylsulfoxide, oleic acid and ethylene glycols. The composition may further contain diclofenac and in one preferred embodiment contains no Hyaluronic acid.
