A traditional Chinese medicine compound combination with the anti-prostate cancer effect and its application. The traditional Chinese medicine compound combination comprises the following traditional Chinese medicine raw materials by weight: 4 to 12 parts of bark of Ailanthus altissima, 12 to 30 parts of Hedyotis diffusa, 3 to 15 parts of Curcuma zedoaria, 15 to 30 parts of Salvia miltiorrhiza, 5 to 15 parts of Prunella vulgaris, and 4 to 12 parts of Glycyrrhiza uralensis. For the traditional Chinese medicine compound combination with the anti-prostate cancer effect, the materials are selected and combined according to the theory of traditional Chinese medicine and the pathogenesis of prostate cancer, and the proportions of the components are scientific and reasonable. Results of pharmacology experiments and clinical experiments show that the traditional Chinese medicine compound has a good anti-prostate cancer effect, and not only can significantly inhibit the proliferation and growth of prostate cancer, but also can inhibit the migration, invasion, and metastasis of prostate cancer, significantly improves the quality of life of a tumor-burdened mice, and improves immune indexes of the tumor-burdened mice. In addition, administration of the compound is convenient and simple, and the compound brings no obvious adverse reaction. The traditional Chinese medicine compound can be developed as a new-generation anti-prostate cancer drug, and is expected to become an effective prescription for the treatment of prostate cancer.L'invention concerne une combinaison de composés issus de la médecine traditionnelle chinoise possédant une efficacité contre le cancer de la prostate, et son application. La combinaison de composés issus de la médecine traditionnelle chinoise comprend les matières premières issues de la médecine traditionnelle chinoise suivantes, en poids : 4 à 12 parties d'écorce d'Ailanthus altissima, 12 à 30 parties d'Hedyotis diffusa, 3 à 15 parties de Curcuma ze