A new and distinct Pyrus communis L. pear tree variety named ‘PE4UNIBO’ is particularly characterized by the following features: medium vigorous trees with semi-upright habit bearing habitus mainly on 1 year old shoots and subsequently on 2-3 years old branches (like ‘Bartlett’) partial grafting incompatibility with quince rootstocks medium late ripening (about 15 days after ‘Bartlett’) medium productivity big size of the fruit (about 300 g) with pyriform-elongated shape (like ‘Abbé Fétel’) yellow-green skin with a nice red over-color on 70-80% of surface tender and juicy white flesh, at full ripening stage and with a very good flavor and sweet taste long storage capacity in cold room up to 6 months.