PASTOR-FERNANDEZ, JOAQUIN,BARTOLOME-NEBREDA, JOSE MANUEL,MACDONALD, GREGOR JAMES,CONDE-CEIDE, SUSANA,DELGADO-GONZALEZ, OSCAR,VANHOOF, GRETA CONSTANTIA PETER,VAN GOOL, MICHIEL LUC MARIA,MARTIN-MARTIN,
申请号：
CA2778949
公开号：
CA2778949C
申请日:
2010.10.27
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention relates to novel imidazo[1,2-b]pyridazine derivatives which are inhibitors of the phosphodiesterase 10 enzyme (PDE10) and which are useful for the treatment or prevention of neurological, psychiatric and metabolic disorders in which the PDE10 enzyme is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, to the use of such compounds or pharmaceutical compositions for the prevention or treatment of neurological, psychiatric and metabolic disorders and diseases.
