LECLERCQ, LAURENT CHRISTIAN L.,BARTOLOME-NEBREDA, JOSE MANUEL,CONDE-CEIDE, SUSANA,VAN GOOL, MICHIEL LUC MARIA
申请号:
CA2875057
公开号:
CA2875057A1
申请日:
2013.07.08
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention relates to novel imidazo[1,2-b]pyridazine and imidazo[1,2-a]-pyrazine derivatives which are inhibitors of the phosphodiesterase 10 enzyme (PDE10) and which may be useful for the treatment or prevention of neurological, psychiatric and metabolic disorders in which the PDE10 enzyme is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, to the use of such compounds or pharmaceutical compositions for the prevention or treatment of neurological, psychiatric and metabolic disorders and diseases.