Dave S.B. Hoon,Donald L. Morton,Connie G. Chiu,Kelly Chong
申请号：
US14401076
公开号：
US20150140039A1
申请日:
2013.05.16
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention concerns embodiments for determining whether an individual in need of immunotherapy will be responsive to the immunotherapy. Determination of one or more SNPs in particular genes is predictive of responsiveness to immunotherapy, particularly in individuals that have melanoma, for example. In certain embodiments, the SNPs are in ITGB2, SP1 1O, ILIB, IL23R, SLC11A1, IL12B, CCR5, TNF, ILIO, CXCL12, BTNL2, ANKRD20A4, CD 14, P2X7, IL8, TLR2, and/or CD209.
