The present disclosure relates to amine-substituted heterocyclic compounds. The present disclosure also relates to pharmaceutical compositions containing these compounds and methods of treating a disorder (e.g., cancer) via inhibition of a methyltransferase enzyme selected from EHMT1 and EHMT2, by administering an amine-substituted heterocyclic compound disclosed herein or a pharmaceutical composition thereof to subjects in need thereof. The present disclosure also relates to the use of such compounds for research or other non-therapeutic purposes.本揭示係關於胺取代的雜環化合物。本揭示亦關於含有該等化合物之醫藥組合物，及經由抑制選自EHMT1及EHMT2之甲基轉移酶來治療病症(例如癌症)之方法，該方法係藉由向有需要之個體投與本文中所揭示之胺取代的雜環化合物或其醫藥組合物。本揭示亦關於此等化合物用於研究或其他非治療性目的之用途。
