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Incremental Dose Finding in Controlled-Release PTH Compounds
专利权人:
Ascendis Pharma Bone Diseases A/S
发明人:
David Brian Karpf,Ken nett Sprogøe,Lars Holten-Andersen
申请号:
US16337803
公开号:
US20190224329A1
申请日:
2017.09.28
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention relates to pharmaceutical compositions comprising a controlled-release PTH compound or a pharmaceutically acceptable salt, hydrate, or solvate thereof, for use in a method of treating, controlling, delaying or preventing a condition which can be treated, controlled, delayed or prevented with PTH, wherein the pharmaceutical composition comprising the controlled-release PTH compound is administered in accordance with a dosage regimen in which dose adjustment in response to hypocalcemia or hypercalcemia is performed in increments of no more than 25%.
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