PYRIDAZINONVERBINDUNG, VERFAHREN ZU IHRER HERSTELLUNG, PHARMAZEUTISCHE ZUSAMMENSETZUNG DARAUS UND IHRE VERWENDUNG

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专利权人:

Shanghai Institute of Materia Medica; Chinese Academy of Sciences

发明人:

HU, Youhong,ZUO, Jianping,LU, Dong,YANG, Li,ZENG, Limin,LIU, Feifei,ZHANG, Yunzhe,CHEN, Wuhong,TONG, Xiankun

申请号：

EP18845225

公开号：

EP3666767A4

申请日:

2018.08.10

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

Provided are a phthalazinone compound, method for preparation thereof, pharmaceutical composition thereof, and a use thereof； the structure of said phthalazinone compound is as represented by formula I； the compound of said formula I is targeted to a viral nucleocapsid； it can inhibit the replication of a virus by means of interference of the viral nucleocapsid, has a potent activity for inhibiting HBV DNA replication and a good liver targeting, can stably exist and enrich in the liver, and is a new and effective anti-HBV inhibitor.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/