Karen Ann Bell,Christophe C. Galopin,Jay Patrick Slack,Lori W. Tigani
申请号：
US11990103
公开号：
US09452982B2
申请日:
2006.08.14
申请国别(地区):
US
年份:
2016
代理人:
摘要：
A method of providing a cooling effect to a product includes the incorporation into the product of at least one compound of the formula Iin which m is a number between 0 and 2, X, Y and Z are selected independently from the group consisting of H, halogen, OH, Me, Et, MeO and EtO, and R1, R2 and R3together comprise at least 6 carbons, selected such that(a) (i) R1 is selected from the group consisting of H, Me, Et, isopropyl and C4-C5 branched alkyl and (ii) R2 and R3 are independently selected from the group consisting of Me, Et, isopropyl and C4-branched alkyl or(b) any two or all of R1, R2 and R3 together form a monocyclic, bicyclic or tricyclic radical having up to 10 carbons.The compounds confer substantial cooling effects on compositions applied to the skin or taken orally, such as toothpastes, mouthwashes, foodstuffs, beverages, confectionery, tobacco products, skin creams and ointments.
