Robert R. Salzler;Nicholas J. Papadopoulos;Michael L. LaCroix-Fralish;Andrew J. Murphy;Lynn MacDonald;Marc R. Morra
发明人:
Lynn MacDonald,Andrew J. Murphy,Nicholas J. Papadopoulos,Marc R. Morra,Robert R. Salzler,Michael L. LaCroix-Fralish
申请号：
US13325098
公开号：
US08425907B2
申请日:
2011.12.14
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides methods for treating pruritus by blocking human protease activated receptor-2 (PAR2) activity. The methods of the invention can be used to treat pruritus associated with atopic dermatitis, psoriasis, burn scarring, hypertrophic scarring, keloids, renal failure or hepatic failure. The methods of the invention include administering an antibody or antigen-binding fragment thereof that specifically binds human PAR2.
