Abhishek Chauhan,Patricia Frances Lalor,Stephen Paul Watson
申请号:
US16331013
公开号:
US20190209680A1
申请日:
2016.09.06
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention relates to the treatment or prophylaxis of acute liv-failure. More particularly, the invention relates to use of an agent that modulates the podoplanin pathway, such as by inhibiting an interaction of podoplanin with CLEC-2 or inhibiting the activity of Src and/or Syk family kinases for the treatment or prophylaxis of acute liver failure, as well as a method for determining the efficacy of treatment of acute liver failure.