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METHOD FOR KEEPING AN AVAILABILITY OF AN IMMUNOGENIC COMPOSITION FOR ANIMAL INJECTION
专利权人:
ИНТЕРВЕТ ИНТЕРНЭШНЛ Б.В. (NL)
发明人:
ВИССЕР Николас (NL),ЯНСЕН Теодорус (NL)
申请号:
RU2011151629/15
公开号:
RU2011151629A
申请日:
2010.05.18
申请国别(地区):
RU
年份:
2013
代理人:
摘要:
1. A method of maintaining the availability of an immunogenic composition for administration to an animal, wherein said composition comprises an antigen and an emulsion, which is a single emulsion at a first temperature below the body temperature of the animal, and said emulsion is drawn at a second temperature between the first temperature and body temperature, where the method comprises: providing the composition, - freezing the composition and - storing the frozen composition until it is needed for administration to the animal. 2. The method according to claim 1, characterized in that the immunogenicity of the immunogenic composition is established before storage. The method according to claim 1 or 2, characterized in that the composition is supplied to a third party upon request, before it is frozen. The method according to claim 1 or 2, characterized in that the composition is supplied to a third party at its request after it has been frozen. The method according to claim 1, characterized in that the composition is frozen through the use of a quick freezing process. The method according to claim 5, characterized in that the composition is frozen in a compressor type freezer. The method according to claim 1, characterized in that the freezing occurs at approximately -20 ° C. The method according to claim 1, characterized in that the composition is stored for more than 4 months, specifically more than 12 months. The method according to claim 1, characterized in that the single emulsion is an oil-in-water emulsion. The method according to claim 9, characterized in that the oil contains a mixture of mannidoleate and mineral oil. The method according to claim 1, characterized in that the antigen is a foot and mouth disease antigen (FMD). A method for testing an immunogenic composition for administration to an animal, wherein the composition comprises1. Способ сохранения доступности иммуногенной композиции для введения животному, где указанная композиция содержит ант
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