Pedersen, Jan Torleif,Kjærgaard, Kristian,Pedersen, Lars Østergaard,Asuni, Abdur-Rasheed,Rosenqvist, Nina Helen,Juhl, Karsten,Tagmose, Lena,Marigo, Mauro,Jensen, Thomas,Christensen, Søren,David, Laur
申请号:
AU2017295608
公开号:
AU2017295608A1
申请日:
2017.07.07
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The present invention relates to a class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396) with improved affinity, as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer s disease and other tauopathies.