Indiana University Research and Technology Corporation
发明人:
Jian-Ting Zhang,Liu Jing-Yuan
申请号:
US16716574
公开号:
US20200222398A1
申请日:
2019.12.17
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Methods for treating various cancers by administering one or more compounds that target the dimeric protein survivin are disclosed. Pharmaceutical compositions containing such compounds are also disclosed, along with general methods of identifying anti-cancer compounds that target oncogenic dimeric proteins. Exemplary compounds that can be used in the disclosed methods of treatment and pharmaceutical compositions have the chemical structure: