Disclosed is a substrate of a three-layer structure which is composed of an inner fibrous layer for holding a plaster thereon, a film layer having through-holes formed therein, and an outer fibrous layer which has air permeability and with which the plaster or a liquid component that has oozed out from the plaster is prevented from leaking out. Also disclosed is a water-containing adhesive patch obtained using the substrate, the adhesive patch being wearable for a long period.