A dry powder drug-dosing device comprises a flow passage member (10), a drug powder storage container (19), and a drug-dosing metering component. A drug powder storage container (19), an annular manual rotation portion (3) and a rotational slide passage (23) are disposed on the outer surface of the housing. A sliding block (26) is disposed at an inner side of the annular manual rotation portion (3) A stirring gear (28) disposed on a transmission sleeve (27) is fit with the raised vibration tooth (21), so as to form a vibration component for enabling an outlet of the inverted conical drug powder storage container (19) to generate vibration. The dry powder drug-dosing device is applicable to the inhalation administration of various medicines in the form of dry powder.