PETIT ARNI ASYMETRIQUE PERMETTANT D'INHIBER L'EXPRESSION D'UN GENE CIBLE DE PERTE DE CHEVEUX MASCULINE

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专利权人:

INC.;OLIX PHARMACEUTICALS

发明人:

HONG, SUN WOO,HWANG, JIHYE

申请号：

CA3054001

公开号：

CA3054001A1

申请日:

2018.02.21

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The present invention relates to an asymmetric siRNA which inhibits an expression of male pattern hair loss target genes and a use thereof and, more particularly, to an asymmetric siRNA which inhibits an expression of 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (SRD5A1) gene, 3-oxo-5-alpha-steroid 4-dehydrogenase 2 (SRD5A2) gene or androgen receptor (AR) gene, and a composition for prevention or treatment of hair loss comprising the asymmetric siRNA.

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