HAWLEY, RONALD CHARLES,IBRAHIM, PRABHA,FORD, ANTHONY P.,GEVER, JOEL R.
申请号:
CA3018180
公开号:
CA3018180A1
申请日:
2017.03.20
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present disclosure provides pyrimidine compounds of Formula 1 and uses thereof, for example, for the potential treatment of diseases associated with P2X purinergic receptors. In certain aspects, the present disclosure provides P2X3 and/or P2X2/3 antagonists which are useful, for example, for the potential treatment of visceral organ, cardiovascular and pain-related diseases, conditions and disorders.