HAWLEY, Ronald Charles,IBRAHIM, Prabha,FORD, Anthony, P.,GEVER, Joel, R.
申请号：
EP17881179
公开号：
EP3554504A4
申请日:
2017.12.11
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
Disclosed herein are substituted pyrazole-pyrimidine compounds of Formula (I) and variants thereof for the treatment, for example, of diseases associated with P2X purinergic receptors. In one embodiment, the P2X3 and/or P2X2/3 antagonists disclosed herein are potentially useful, for example, for the treatment of visceral organ, cardiovascular and pain-related diseases, conditions and disorders.
