JÉRÔME EMILE GEORGES GUILLEMONT,DAVID FRANCIS ALAIN LANÇOIS,ELISABETH THÉRÈSE JEANNE PASQUIER,KOENRAAD JOZEF LODEWIJK MARCEL ANDRIES,ANIL KOUL
申请号：
MYPI 20063590
公开号：
MY148219A
申请日:
2006.07.26
申请国别(地区):
MY
年份:
2013
代理人:
摘要：
THE PRESENT INVENTION RELATES TO NOVEL SUBSTITUTED QUINOLINE DERIVATIVES ACCORDING TO THE GENERAL FORMULA (IA) OR FORMULA (IB ): OR THE PHARMACEUTICALLY ACCEPTABLE ACID OR BASE ADDITION SALTS THEREOF, THE QUARTERNARY AMINES THEREOF, THE STEREOCHEMICALLY ISOMERIC FORMS THEREOF, THE TAUTOMERIC FORMS THEREOF AND THE N-OXIDE FORMS THEREOF. THE CLAIMED COMPOUNDS ARE USEFUL FOR THE TREATMENT OF A BACTERIAL DISEASE INCLUDING A MYCOBACTERIAL DISEASE, PARTICULARLY THOSE DISEASES CAUSED BY PATHOGENIC MYCOBACTERIA SUCH AS MYCOBACTERIUM TUBERCULOSIS, M BOVIS, M. AVIUM AND M. MARINUM. ALSO CLAIMED IS A COMPOSITION COMPRISING A PHARMACEUTICALLY ACCEPTABLE CARRIER AND, AS A ACTIVE INGREDIENT, A THERAPEUTICALLY EFFECTIVE AMOUNT OF THE CLAIMED COMPOUNDS, THE USE OF THE CLAIMED COMPOUNDS OR COMPOSITIONS FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF BACTERIAL DISEASES AND A PROCESS FOR PREPARING THE CLAIMED COMPOUNDS.
