A cuff system includes a flexible substantially tubular sheath having a distal end, a proximal end, a central longitudinal axis, and a central channel extending along the longitudinal axis. The system also includes a first guide disposed at the proximal end of the sheath. The first guide is configured to control insertion of a cuff connector into the central channel in a first direction substantially parallel to the longitudinal axis. The system further includes an orifice proximate the distal end of the sheath. The orifice is configured to enable fluid connection between a portion of the cuff connector and an inflatable cuff while a remainder of the cuff connector is disposed within the central channel.