An automatic injection device (10) containing a pre-loaded charge of medicament for automatically self-administering medication the following actuation thereof, the device comprising: a housing (110) a medicament chamber (150, 350) arranged in the housing (110), the medicament chamber (150, 350) 5 includes a first compartment (152) containing a portion of dry medicament, and a second compartment (151) It contains a wet medicament portion to be mixed with the dry medicament portion one sealing structure (160, 360) between the first compartment (152) and the second compartment (151), seal structure (160, 360) that is initially in a separate sealing state that maintains the first compartment (152) of second compartment (151), seal structure (160, 360) including: at least one flow path (167) formed therein, a needle assembly (140, 340) dispenses medicament portions mixed camera drug (150, 350) and an activation assembly (120) carried by the housing (110) and including a stored energy source, wherein activation of the activation assembly (120) releases the stored energy from the stored energy source, causing the seal structure (160, 360) through the sealing state to the state of mixing, and causing or allowing therefore the medicament portions are mixed and are forced through the needle assembly (140, 340), wherein the seal structure (160, 360) includes an annular scraper ring arranged at the front end of the seal structure (160, 360) and positioned to engage movably with the inner walls of the first compartment (152) as portion seal structure (160, 360) is moved through said first component (152), said wiper portion being configured to route particles radially inwardly medicatio to dry coupled with the inner walls as the seal structure (160, 360) moves through the first compartment (152).Un dispositivo automático de inyección (10) que contiene una carga precargada de medicamento para la autoadministración automática de medicamento tras la actuación del mismo, dispositiv
