An automatic applicator for liquid pharmaceutical preparations particularly for insulin more particularly for multiple injection application of set doses of a medicine from an exchangeable container comprising a body housing (1) connected to a housing (2) of an exchangeable container with a medicine particularly insulin having a plunger (12) suitable for expelling the medicine the said plunger (12) being displaced only linearly by means of an integrated driving unit suitable for immobilising driving leading linearly and blocking rotation of the said plunger (12) driven via a double action clutch by a tensioning spring (15) situated in the body housing (1) the said spring (15) tensioned by a rotary hand-dose-setting ring (3) via the same double action clutch unit wherein the said driving unit is activated by a trigger unit (13) and a dose is indicated by an indicating arrangement