The present invention relates to macrocyclic indole derivatives of general formula(I):,in which R1, R2, R3, R4, R5, R6, A and L are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.本發明係關於通式(I)之巨環吲哚衍生物：，其中R1、R2、R3、R4、R5、R6、A及L係如本文所定義；製備該等化合物之方法；適用於製備該等化合物之中間化合物；包含該等化合物之醫藥組合物及組合；及該等化合物作為單獨藥劑或與其他活性成分組合用於製造供治療或預防疾病，特別是過度增生性病症之醫藥組合物的用途。
