The present invention covers 3,9-diazaspiro[5.5]undecane compounds of general formula (I) and general formula (I-a):and,in which R1, R2, R3and R4are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment and/or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.本發明涵蓋通式(I)及通式(I-a)之3,9-二氮雜螺[5.5]十一烷化合物，及，其中R1、R2、R3及R4係如本文所定義；製備該等化合物之方法、可用於製備該等化合物之中間體化合物、包括該等化合物之醫藥組合物及組合以及該等化合物用以製造用於作為唯一藥劑或與其他活性成分組合來治療及/或防治疾病、尤其過度增殖性病症之醫藥組合物之用途。
