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Compound with spiro chiral carbon backbone, preparation method thereof, and pharmaceutical composition containing the same
专利权人:
Jeong-Ho Hong;Jae-Hwan Lee;Eun-O Kim;Chan-Soo Shin;Heon-Joong Kang;Seung-Bum Park;Jeong-Ah Kim;Jung-Rae Rho;Sang-Mi Oh;Jun-Young Hong
发明人:
Heon-Joong Kang,Jung-Rae Rho,Jeong-Ho Hong,Seung-Bum Park,Chan-Soo Shin,Jae-Hwan Lee,Jun-Young Hong,Eun-O Kim,Jeong-Ah Kim,Sang-Mi Oh
申请号:
US13126979
公开号:
US08703813B2
申请日:
2009.10.30
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Provided is a compound having a spiro chiral carbon backbone, a stereoisomer thereof, an enantiomer thereof, an in vivo hydrolysable precursor thereof, or a pharmaceutically acceptable salt thereof. The compound having the spiro chiral carbon backbone has excellent osteoblast differentiation activity, mast cell inhibitory activity, and fatty acid synthesis inhibitory activity in the liver. Therefore, the compound can be expected to play an innovative role in treatment of osteoporosis, fatty liver, and obesity.
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中国工程科技知识中心
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