A vaccine composition comprising a protein, which can be detected in Haemophilus influenzae, having an amino acid sequence as described in SEQ ID NO: 1, or a fragment thereof, is described. The fragment comprises an amino acid sequence having at least 15 contiguous amino acids from the amino acid sequence of SEQ ID NO: 1, and the fragment (if necessary when coupled to a carrier) is capable of raising an immune response which recognises the polypeptide of SEQ ID NO: 1.
