A medical manipulator includes a surgical tool that has an end effector at a distal end and a drive unit that is detachable from a handle of the surgical tool. In a state where the drive unit is mounted on the handle, when a manipulation lever is manipulated, a driving force of a motor is transmitted to the handle, and the end effector is operated. Even in a state where the drive unit is detached from the handle, the surgical tool can be independently used by a manual manipulation.