Botella, Gabriel Martinez,Harrison, Boyd L.,Robichaud, Albert Jean,Salituro, Francesco G.,Beresis, Richard Thomas
申请号:
AU2019213394
公开号:
AU2019213394A1
申请日:
2019.08.08
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
#$%^&*AU2019213394A120190829.pdf#####ABSTRACT Provided herein are 3,3-disubstituted 19-nor-steroidal compounds according to Formula (I): A R3 b O R 3b 2 H H R2 Hd ~R 4a R 4b and pharmaceutical compositions thereof. Such compounds are contemplated useful for the 5 prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, schizophrenia spectrum disorders, disorders of memory and/or cognition, movement disorders, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and/or withdrawal syndromes, tinnitus, and status epilepticus. 10 1