STEPHEN WILLIAM CLARIDGE,LJUBOMIR ISAKOVIC,MICHAEL MANNION,STÉPHANE RAEPPEL,OSCAR MARIO SAAVEDRA,FRÉDÉRIC GAUDETTE,LIJIE ZHAN,NANCY Z. ZHOU,FRANCK RAEPPEL,ROBERT DEZIEL,ARKADII VAISBURG,TETSUYUKI UNO
申请号：
BRPI0816064
公开号：
BRPI0816064A2
申请日:
2008.08.28
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
This invention relates to compounds that inhibit protein tyrosine kinase activity. In particular the invention relates to compounds that inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of VEGF receptor signaling and HGF receptor signaling. More particularly, the invention relates to compounds, compositions and methods for the inhibition of VEGF receptor signaling and HGF receptor signaling. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
