CLARIDGE, Stephen William,ISAKOVIC, Ljubomir,MANNION, Michael,RAEPPEL, Stéphane,SAAVEDRA, Oscar Mario,GAUDETTE, Frédéric,ZHAN, Lijie,ZHOU, Nancy Z.,RAEPPEL, Franck,DEZIEL, Robert,VAISBURG, Arkadii,UNO
申请号:
DK08800252
公开号:
DK2183254T3
申请日:
2008.08.28
申请国别(地区):
DK
年份:
2017
代理人:
摘要:
This invention relates to compounds that inhibit protein tyrosine kinase activity. In particular the invention relates to compounds that inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of VEGF receptor signaling and HGF receptor signaling. More particularly, the invention relates to compounds, compositions and methods for the inhibition of VEGF receptor signaling and HGF receptor signaling. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.