Pyrethrin [1,5-a] pyrethroid, protein inhibitor Kinasa TRK； pharmacological synthesis； intermediate compounds； tools for the treatment of thyroid cancer, pancreatic cancer, colon cancer and breast cancer, etc.
MOLTENI, VALENTINA,FAN YI,LOREN JON,SMITH JEFFREY M,FLATT BRENTON T
申请号：
CL2013002430
公开号：
CL2013002430A1
申请日:
2013.08.22
申请国别(地区):
CL
年份:
2013
代理人:
摘要：
The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated TRK kinase activity. wherein: A is X1 is CH or N；COMPUESTOS DERIVADOS DE PIRAZOLO[1,5-A]PIRIDINA, INHIBIDORES DE PROTEINA KINASA TRK； COMPOSICION FARMACEUTICA； COMPUESTO INTERMEDIARIOS； UTILES PARA EL TRATAMIENTO DE CARCINOMA PAILAR DE TIROIDES, CANCER DE PANCREAS, CANCER DE COLON Y CARCINOMA DE MAMA, ENTRE OTRAS.
