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4-(3-fluorophenyl)-1-(4-methylimidazol-5-yl)thiosemicarbazide, method of preparation and medical use
专利权人:
UNIWERSYTET MEDYCZNY W LUBLINIE;UNIWERSYTET ŁÓDZKI
发明人:
LIDIA WĘGLIŃSKA,MONIKA WUJEC,AGATA PANETH,KATARZYNA DZITKO,ADRIAN BEKIER,BOŻENA DZIADEK,WĘGLIŃSKA, LIDIA,WUJEC, MONIKA,PANETH, AGATA,DZITKO, KATARZYNA,BEKIER, ADRIAN,DZIADEK, BOŻENA
申请号:
PL426153
公开号:
PL235166B1
申请日:
2018.06.29
申请国别(地区):
PL
年份:
2020
代理人:
摘要:
The scope of the notification is 4-(3-fluorophenyl)-1-(4-methylimidazol-5-yl)thio-semicarbazide, as outlined in the drawing. The notification shall also include the following: the relationship and mode of its production, which is that 4-methyl-5-imidazole-5-carboxylic acid hydrazide undergoes an isothiocyanate reaction with a molar ratio 1:1, the reaction is carried out in an anhydrous ethanol environment at the boiling point of the solvent favourably when the reaction time is 30-min.,the product obtained is then cooled,the precipitated sediment is drained,and crystallizes after drying.
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