The present invention relates to a plasma-generating device comprising an anode, a cathode and an elongate plasma channel which extends substantially in the direction from said cathode to said anode. The plasma channel has a throttling portion which is arranged in said plasma channel between said cathode and an outlet opening arranged in said anode. Said throttling portion divides said plasma channel into a high pressure chamber, which is positioned on a side of the throttling portion closest to the cathode, and has a first maximum cross-sectional surface transversely to the longitudinal direction of the plasma channel, and a low pressure chamber, which opens into said anode and has a second maximum cross-sectional surface transversely to the longitudinal direction of the plasma channel, said throttling portion having a third cross-sectional surface transversely to the longitudinal direction of the plasma channel which is smaller than said first maximum cross-sectional surface and said second maximum cross-sectional surface. Moreover at least one intermediate electrode is arranged between said cathode and said throttling portion. The invention also relates to a plasma surgical device, use of such a plasma surgical device in surgery and a method of generating a plasma.