The present invention relates to the field of the chemical medicines and in particular to purinyl N hydroxyl pyrimidine formamide derivatives a preparation method therefor and a use thereof. The present invention provides a purinyl N hydroxyl pyrimidine formamide derivative having a structure represented by formula (I). The invention also provides a method for preparing said purinyl N hydroxyl pyrimidine formamide derivative and a use thereof. Purinyl N hydroxyl pyrimidine formamide derivative provided in the invention can be not only a PI3K and HDAC double functional target kinase inhibitor but also a PI3K or HDAC single target kinase inhibitor thus providing new choice for preparing multi target inhibitors.
