Philip Scuderi, Jr.,Vikram Arora,Jennifer A. Hunt,Valery Novokhatny,Stephen R. Petteway, Jr.
申请号：
US12090782
公开号：
US08231869B2
申请日:
2006.10.18
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Methods of using polynucleotides and polypeptides relating to a recombinantly-modified plasmin(ogen) molecule are provided, including methods related to vitrectomy or vitreolysis. The plasmin(ogen) molecule has a single kringel domain N-terminal to the activation site present in the native human plasminogen molecule, and exhibits lysine-binding and significant enzymatic characteristics associated with the native enzyme.
