The invention includes monoclonal and polyclonal antibodies, and antigen-binding fragments thereof, having specific binding affinity for 4,6-diamino-5-(formylamino)pyrimidine (FAPY-adenine)； hybridomas producing such antibodies； immunoconjugates comprising an antibody or antigen-binding fragment of the invention coupled to a moiety； and in vitro and in vivo methods for using such antibodies, antibody fragments, and conjugates based on binding to FAPY-adenine； nucleic acids encoding the heavy and/or light chains of the antibodies； vectors comprising the nucleic acid sequences encoding the heavy and/or light chains； host cells comprising and, optionally, expressing the nucleic acid sequences； and methods for the production of the aforementioned materials.
